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In response to the TNFα treatment
leading to cell proliferation and polyploidization stopped
VUN65671 was reported in Journal of Medicinal Chemistry (2020)
In HCT116 colorectal carcinoma cell line
KU-0063794 inhibits cell growth of both wild-type and mLST8-deficient MEFs and induces a G1 cell cycle arrest
Ogerin Catalog No.:M15233-2 In response to the TNFαOgerin is a selective GPR68 positive allosteric modulator, with a pEC50 of 6. 83. Ogerin shows inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptoor and weak antagonist activity (Ki, 736 nM) at 5 HT2B receptor. Ogerin blocks recall in fear conditioning in mice. Product information CAS Number: 1309198 71 7 Molecular Weight: 307. 35 Formula: C17H17N5O Chemical Name: {2 [4 amino 6 (benzylamino) 1,3,5 triazin 2 yl]phenyl}methanol Smiles: